Adam "Pacman" Jones picked off Brady's desperation pass inside the 5-yard line with 16 seconds left to clinch it.
Brady had thrown a touchdown pass in 52 straight games, second-longest in NFL history behind Drew Brees. The Patriots were held out of the end zone for the first time since a 16-9 loss to the Jets on Sept. 20, 2009.
CHIEFS 26, TITANS 17
NASHVILLE, Tenn. (AP) — Jamaal Charles scored a 1-yard touchdown with 6:23 left, and the Chiefs rallied to keep up their perfect start.
The Chiefs (5-0) are off to their best start since 2003, when they won their first nine games. This win came despite blowing a 13-0 halftime lead in this early AFC showdown between these surprising teams bouncing back after losing seasons.
The Titans (3-2) couldn't have been more out of synch in the first half with Ryan Fitzpatrick starting for Jake Locker, sidelined with his sprained right hip. He missed his first five passes and went three-and-out on his first five series before guiding Tennessee to 17 straight points in the second half.
Charles put the Chiefs ahead to stay, and they intercepted Fitzpatrick twice in the final 6:14. Ryan Succop kicked four field goals, including a 48-yarder.
RAVENS 26, DOLPHINS 23
MIAMI GARDENS, Fla. (AP) — Justin Tucker kicked a 44-yard field goal to put the Baltimore Ravens ahead with 1:42 left, and they withstood a frantic comeback bid.
Ryan Tannehill completed a 46-yard pass to Brandon Gibson on fourth down to keep Miami's hopes alive, but Caleb Sturgis then missed a 57-yard field goal attempt wide left with 33 seconds to go.
The Ravens (3-2) bounced back from a loss last week at Buffalo and won on the road for the first time this season. The Dolphins (3-2) lost their second game in a row.
Baltimore moved 34 yards to set up Tucker's game-winning field goal, his fourth of the day. The Ravens ran for a season-high 133 yards, and Joe Flacco threw for 269 yards.