"Obviously, it hurts. It hurts me. It hurts the guys in that room" Bills coach Doug Marrone said. "I'm not going to stand here and say we should've won that game because we obviously didn't. But it hurt."
Here's five things that made the difference as the Chiefs snapped a six-game losing streak at Orchard Park, dating to 1986.
HAPPY RETURNS: The Chiefs' defense has scored six times this season.
Smith's TD matched the second-longest interception return in team history, and he was too tired to enjoy it.
"Do you know how long 100 yards is?" Smith said. "I was definitely happy I made it. I wanted to celebrate, but I was so tired."
Hali scored to put the Chiefs up 20-13 with 12:47 left. He scooped up a loose ball after cornerback Marcus Cooper punched the ball out of receiver T.J. Graham's hands.
TUEL TIME: Tuel's first NFL start began well before faltering late. The undrafted rookie from Washington State got his first career touchdown — a 59-yard connection to fellow rookie Marquise Goodwin — as he finished the first quarter going 5 of 7 for 112 yards. Tuel struggled the rest of the way, going 13 of 32 for 117 yards with two interceptions.
He started in place of interim starter Thad Lewis (bruised ribs) and with rookie starter EJ Manuel missing his fourth game with a sprained right knee.
"Did Jeff play well enough for us to win?," Marrone asked. "At times. At times he didn't. I think you could say that about a lot of people."
ON THE RUN: Led by C.J. Spiller's 116 yards rushing, the Bills managed a season-best 241 yards against the NFL's 10th-best rushing defense. Spiller, who returned after missing one game with a sprained left ankle, had runs of 61 and 29 yards. He also caught two passes for 39 yards, giving him 155 yards from scrimmage.