Sonny Gray (3-1) allowed three runs and five hits in seven innings. He had won six straight regular-season decisions dating to September.
WHITE SOX 6, TIGERS 4
DETROIT (AP) — Marcus Semien's seventh-inning grand slam lifted Chicago over Detroit.
Jose Abreu hit another long home run for the White Sox, but it was Semien's first career slam that turned around the game. Detroit starter Drew Smyly allowed two runs in six innings, but Evan Reed (0-1) gave up two singles and a walk, and Ian Krol allowed the home run to Semien.
Andre Rienzo (1-0) gave up four runs in the fourth inning, but kept the Tigers quiet otherwise in his first start this season. He allowed five hits and two walks in 6 1-3 innings, striking out three.
Matt Lindstrom pitched the ninth for his third save
INDIANS 5, ROYALS 3
CLEVELAND (AP) — Jason Kipnis drove in Nick Swisher with a two-out double in the seventh inning, sending Cleveland past Kansas City.
Kipnis ripped his double off Kelvin Herrera (0-1) into the gap in right-center, deep enough to easily score Swisher, who reached on a two-out single. The Indians tacked on an insurance run in the eighth on pinch-hitter Lonnie Chisenhall's bloop RBI single.
Bryan Shaw (1-0) finished the seventh and got one out in the eighth. Cody Allen retired two, and John Axford worked the ninth for his AL-leading eighth save.
Salvador Perez and Mike Moustakas hit back-to-back homers in the second for Kansas City.
ORIOLES 10, BLUE JAYS 8
TORONTO (AP) — Nelson Cruz hit two of Baltimore's season-high four home runs and Chris Davis and Matt Wieters also connected fpr the Orioles.
Cruz hit a solo homer off Dustin McGowan in the third and a grand slam off Todd Redmond (0-2) in the fifth, giving him six homers this season and 11 career multihomer games. The slam was his seventh.