"When I was little, my mom in her forties looked like a mom in her forties. We have sort of erased numbers. I have, at least. I think we're also very health-aware," she said. "Nutritionally, we are very aware of what's good for us and what's not good for us, way more than a couple of generations ago. So I think we are learning how to keep our bodies fit and our minds fit and (keep) everything up and running."
She added: "I hate when people tell me 'For your age, you look great.' I can't stand that."
In one memorable scene, Aniston lets co-star Kathryn Hahn get a handful of her breasts. Sudeikis didn't have to deal with anything quite as intimate, though a scene with Nick Offerman penetrating his ear with a wet finger proved to be decidedly uncomfortable.
"It's not enjoyable, per se. I don't mind a Q-Tip in there, but Nick is a man's man. That's a strong, girthy, calloused finger. He was full in there, I couldn't hear anything but my own heartbeat," Sudeikis said as Aniston broke out in laughter.
For Sudeikis, the film may further solidify his box-office appeal outside of "Saturday Night Live." While "Horrible Bosses" was a success, it was also an ensemble comedy. In "We're the Millers," he gets top billing, along with Aniston.
Although Sudeikis has made it official that he won't be returning to "SNL," he said it hasn't sunk in that he's really gone.
"Truth be told, I won't feel it until September and the shows starts up again and I'm not there. Summers off is par for the course," he said.
But the 37-year-old admits to feeling something when his portrait was placed on the wall of former cast members.